Search results for "Serum Globulins"

showing 2 items of 2 documents

Human conglutinin-like protein inhibits infection by the human immunodeficiency virus-1 in vitro.

1992

In summary the lectin-like protein analogous to bovine conglutinin was purified from human serum. Using a lectin-based ELISA system, it was demonstrated that conglutinin-like protein binds to human immunodeficiency virus-1 (HIV1) glycoprotein 120 (gp 120) via its carbohydrate binding site. In vitro experiments with T-lymphoblastoid CEM cells revealed that conglutinin-like protein abolishes infection by HIV1; a 50 % cytoprotective concentration of 23.9 μg/ml was measured.

ImmunologyHIV Envelope Protein gp120Antiviral AgentsVirusConglutininViral envelopeVirologyLectinsHumansBinding sitechemistry.chemical_classificationAcquired Immunodeficiency SyndromebiologyBinding proteinComplement Fixation TestsLectinVirologyMolecular biologyIn vitroCollectinsMannose-Binding Lectinschemistrybiology.proteinHIV-1Serum GlobulinsGlycoproteinCarrier ProteinsMannoseProtein BindingResearch in virology
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Hp, Gc, Cp, Tf, Bg and Pi phenotypes in leprosy patients and healthy controls from West Bengal (India)

1972

On a sample of n=601 leprous individuals and n=386 healthy controls from West Bengal (India) the question is discussed, if there are existing any associations between leprosy and several serum protein groups like haptoglobin, Gc, ceruloplasmin, transferrin, β2 I and Pi. No associations were found concerning the haptoglobins and transferrins. Certain associations came out respecting ceruloplasmin, β2 I and Pi phenotypes. However, these associations, which were found in connection with the different types and clinical courses of leprosy, should be reexamined by further research. The most striking results were obtained concerning the Gc proteins. In accordance with previously performed investi…

Serum proteinIndiaGene FrequencyLeprosyGeneticsmedicineHumansMetabolic diseaseGenetics (clinical)Glycoproteinschemistry.chemical_classificationPolymorphism GeneticHaptoglobinsbiologyHaptoglobinTransferrinCeruloplasminPi phenotypesmedicine.diseasePhenotypechemistryTransferrinImmunologybiology.proteinSerum GlobulinsWest bengalLeprosyFactor Analysis StatisticalCeruloplasminHuman Genetics
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